Category: 4. Health

  • New tools to treat retinal degenerations at advanced stages of disease

    New tools to treat retinal degenerations at advanced stages of disease

    Inherited retinal degenerations (IRDs) are a group of genetic disorders that lead to progressive vision loss as the light-sensing cells of the eye — the photoreceptors — die due to mutations in genes needed for their function and survival.

    Gene therapy has emerged as a promising approach, replacing or supplementing defective genes to preserve or restore vision. Yet, most existing gene therapy strategies have been developed and tested in early disease stages — leaving a major gap in…

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    News Source: www.sciencedaily.com

  • New ketamine study promises extended relief for depression

    New ketamine study promises extended relief for depression

    Roughly 10 percent of the U.S. population is afflicted with major depressive disorder at any given time, and up to 20 percent will exhibit MDD symptoms over their lifetimes.

    Yet despite its prevalence, methods to treat MDD often fall short for a not-insignificant portion of the population. Antidepressants — the standard of treatment — don’t work for 30 percent with MDD.

    When infused at a low dose ketamine shows remarkable efficacy as a rapidly acting antidepressant, with effects observed…

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    News Source: www.sciencedaily.com

  • Researchers develop gene therapy that can target airway and lungs via nasal spray

    Researchers develop gene therapy that can target airway and lungs via nasal spray

    For gene therapy to work well, therapeutic molecules need to be efficiently delivered to the correct locations in the body — a job commonly given to adeno-associated viruses (AAV).

    To improve the AAV’s ability to deliver therapeutics specifically to the lungs and airway, Mass General Brigham researchers developed and applied a new version, called AAV.CPP.16, that can be administered with a nasal spray. In preclinical models, the innovative tool outperformed previous versions by more…

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    News Source: www.sciencedaily.com

  • An artificial protein that moves like something found in nature

    An artificial protein that moves like something found in nature

    The ability to engineer shapeshifting proteins opens new avenues for medicine, agriculture, and beyond.

    Proteins catalyze life by changing shape when they interact with other molecules. The result is a muscle twitching, the perception of light, or a bit of energy extracted from food.

    But this crucial ability has eluded the growing field of AI-augmented protein engineering.

    Now, researchers at UCSF have shown it is possible to make new proteins that move and change shape like those in nature….

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    News Source: www.sciencedaily.com

  • Positive Benefits of Medical Cannabis for Sleep Apnea

    Positive Benefits of Medical Cannabis for Sleep Apnea

    What impact can cannabis have for sleep apnea patients? This is what a recent report from the Office of Cannabis Management hopes to address as a team of researchers investigated the pros and cons of using medical cannabis to treat sleep apnea, which is caused from reduced or paused breathing during sleep, resulting in disruptive sleep, waking up fatigued, and an overall negative impact on well-being.

    For the study, the researchers evaluated 3,102…

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    News Source: www.labroots.com

  • It’s tricky to transplant a bladder. How surgeons finally did it

    It’s tricky to transplant a bladder. How surgeons finally did it

    The first successful human bladder transplant could offer hope for people with bladder problems.

    On May 4, 2025, Oscar Larrainzar, 41, became the first human to successfully receive a bladder transplant. The surgery was part of a clinical trial developed to demonstrate the feasibility of bladder transplants in patients with terminal bladder diseases. The American Cancer Society estimates there will be about 85,000 new cases of bladder cancer in 2025 in the United States,…

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    News Source: www.sciencenews.org

  • Exercise and eat your veggies: Privileged prescriptions like these don’t always reduce risk of heart disease

    Exercise and eat your veggies: Privileged prescriptions like these don’t always reduce risk of heart disease

    A leading cardiovascular disease researcher from Simon Fraser University is ringing the alarm on universal recommendations intended to improve heart health around the globe.

    Cardiovascular disease (CVD) is the leading cause of death worldwide, with 80 per cent of deaths occurring in low- and middle-income countries. However, international heart-health guidelines are primarily based on research from high-income countries and often overlook upstream causes of CVD, says Scott Lear, a health…

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    News Source: www.sciencedaily.com

  • Social connection is still underappreciated as a medically relevant health factor

    Social connection is still underappreciated as a medically relevant health factor

    Research confirms that social isolation and loneliness significantly impact health and mortality, even if not listed on death certificates. BYU psychology and neuroscience professor, Julianne Holt-Lunstad, has published extensively on the topic, including a landmark 2010 meta-analysis and a 2023 framework on assessment and treatment. She also served as lead scientist on the 2023 Surgeon General Advisory and is advising the World Health Organization on an upcoming report that addresses the…

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    News Source: www.sciencedaily.com

  • Tiny genetic switch found to control brain balance and behavior

    Tiny genetic switch found to control brain balance and behavior

    Researchers at the Institute for Basic Science (IBS) have identified a remarkably small but critical piece of genetic code that helps determine how brain cells connect, communicate, and function. The discovery not only deepens our understanding of how the brain’s wiring is built but may also explain the origins of several neurological and psychiatric conditions.

    The study, conducted by the Center for Synaptic Brain Dysfunctions at IBS and led by Director KIM Eunjoon (Distinguished Professor…

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    News Source: www.sciencedaily.com

  • How stress disrupts emotion control in people with mental health conditions

    How stress disrupts emotion control in people with mental health conditions

    New Edith Cowan University (ECU) research suggests that acute stress may impair key brain functions involved in managing emotions — particularly in people living with ‘distress disorders’ such as depression, anxiety, and borderline personality disorder.

    The study by ECU Masters student Tee-Jay Scott and Professor Joanne Dickson found that rather than enhancing mental focus in high-pressure moments, stress may temporarily disrupt executive functions — the brain’s control processes that help…

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    News Source: www.sciencedaily.com