Statins have transformed heart health, saving millions of lives by lowering cholesterol and reducing the risk of heart attacks and strokes. But for many patients, these drugs come with a troubling downside: muscle pain, weakness and, in rare…
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Studies have shown that even a few hours of monocular deprivation can markedly improve the visual function of the deprived eye in adults. However, the underlying neural mechanisms of this ocular dominance plasticity remain unclear.
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Parkinson’s disease (PD) is an age-related, progressive neurodegenerative disorder. The hallmark of PD pathogenesis is the Lewy bodies (LBs) that accumulate in neurons in the substantia nigra region of the brain, damaging these neurons and…
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Scientists have discovered how a mitochondrial mutation rewires immune function in a model of inherited primary mitochondrial disorders, which often lead to severe disability and death. They have discovered that this single inherited mutation…
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Yadav, N., Toader, A. & Rajasethupathy, P. Beyond hippocampus: thalamic and prefrontal contributions to an evolving memory. Neuron 112, 1045–1059 (2024).
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Two adult male rhesus macaques (Macaca mulatta) participated in the experiment. The number of monkeys (2) follows previous work using similar approaches21. Monkeys Si and Ch were between 8 and 11 years old and weighed approximately 12.7…
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Artificial intelligence may write award-winning essays and diagnose disease with remarkable accuracy, but biological brains still hold the upper hand in at least one crucial domain: flexibility.
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Researchers from the Harvard Pilgrim Health Care Institute have produced the first national estimate of how many medical students would be affected by new federal loan restrictions imposed by the 2025 One Big Beautiful Bill Act (OBBBA). Their…
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If watching Robert De Niro ordering hammer-based retribution on a cheat’s hand in “Casino” instinctively made you wince, you are not alone. Many people say that seeing bodily injury on film makes them flinch, as if they “feel” it themselves. It…
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In the face of US federal funding cuts, biomedical researchers propose strategies for continued progress in drug discovery. Publishing in Trends in Pharmacological Sciences, their recommendations include harnessing AI and computational analyses…
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