Trump says paused tariffs will return if trade deals aren't reached.
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News Source: www.aljazeera.com
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Trump warns tariffs will return without trade deals
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Occupation forces assaulted and injured three citizens during their raid on Al-Bireh.
Three citizens were injured on Thursday evening after being severely …
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US stocks down as trade war with China deepens | Donald Trump News
US stocks sunk on Thursday, giving back some of the huge gains that followed President Donald Trump’s decision to temporarily lower his sweeping tariffs on dozens of countries, as investors assessed the status of his global trade war.
Trump’s sudden decision on Wednesday to freeze most of his hefty new duties for 90 days brought relief to battered markets and anxious global leaders, even as he ratcheted up a trade war with China.
But his whipsaw approach still has companies worried about…
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UN: 12,500 patients in Gaza need medical evacuation
The United Nations Office for the Coordination of Humanitarian Affairs …
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Immune protein modification blocks viral replication, heart inflammation
Cleveland Clinic virology researchers have found that a specific protein modification to the immune protein MDA5 is key to how human bodies detect and respond to viruses and viral replication.
The PNASpublication explains how two protein modifications activate MDA5, an essential immune protein, to sense invaders, limit viral replication and fight infections. This process is key to preventing outcomes like virus-induced heart inflammation.
This most recent publication builds on a body of work…
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Brain study increases understanding of what triggers drug use relapse
New research on the biological basis of addiction has found that the critical epigenetic enzyme histone deacetylase 5 (HDAC5) limits the expression of the gene Scn4b, regulating neuronal activity and thereby the formation of strong drug-related memories, which can trigger relapse in individuals with substance use disorders (SUDs). The study in Biological Psychiatry, published by Elsevier, detailing these epigenetic mechanisms in the brain, uncovers a new molecular target for the development…
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Study provides scaffold to selectively target drug breakdown process
Scientists at St. Jude Children’s Research Hospital explored selectively blocking the CYP3A4 protein responsible for breaking down large swaths of approved drugs, providing a way to improve drug efficacy.
Cytochrome P450 (CYP) proteins are responsible for breaking down more than 80% of all Food and Drug Administration (FDA) approved drugs, reducing their effectiveness. However, how to prevent CYPs from doing this without off-target effects has puzzled researchers until now. Scientists at St….
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Scientists develop process using molecules in the cell to identify environmental signals
Scientists have transformed RNA, a biological molecule present in all living cells, into a biosensor that can detect tiny chemicals relevant to human health.
Research by Rutgers University-New Brunswick scientists centers on RNA, a nucleic acid that plays a crucial role in most cellular processes. Their work is expected to have applications in the surveillance of environmental chemicals and, ultimately, the diagnosis of critical diseases including neurological and cardiovascular diseases and…
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New phase of the immune response uncovered
The research groups led by Wolfgang Kastenmüller and Georg Gasteiger employed innovative microscopy techniques to observe how specific immune cells, known as T-cells, are activated and proliferate during a viral infection. Their findings revealed novel mechanisms: the immune system amplifies its defense cells in a far more targeted way than previously believed.
T-Cells Proliferate and Specialize During the Immune Response
T-cells are crucial defense cells in the immune system. To…
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Brain pathway links inflammation to loss of motivation, energy in advanced cancer
The fatigue and lack of motivation that many cancer patients experience near the end of life have been seen as the unavoidable consequences of their declining physical health and extreme weight loss. But new research from Washington University School of Medicine in St. Louis challenges that long-held assumption, showing instead that these behavioral changes stem from specific inflammation-sensing neurons in the brain.
In a study published April 11 in Science, the researchers report that they…
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News Source: www.sciencedaily.com