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  • Light bulb moment for understanding DNA repair switches

    Light bulb moment for understanding DNA repair switches

    Researchers from the University of Birmingham have uncovered answers that provide the detail to explain two specific DNA repair processes that have long been in question.

    The publication of two papers demonstrates how work led by laboratories from the Department of Cancer and Genomic Sciences, and School of Biosciences at the University of Birmingham has made strides in understanding how the repair process is correctly orchestrated.

    The importance of understanding DNA repair

    Our cells…

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    News Source: www.sciencedaily.com

  • Sleep matters: Duration, timing, quality and more may affect cardiovascular disease risk

    Sleep matters: Duration, timing, quality and more may affect cardiovascular disease risk

    Healthy sleep includes multiple components, such as number of hours of sleep per night, how long it takes to fall asleep, daytime functioning and self-reported sleep satisfaction, and addressing these different dimensions of sleep may help to reduce cardiometabolic health and related risk factors, according to a new American Heart Association scientific statement published today in Circulation: Cardiovascular Quality and Outcomes.

    The new scientific statement, “Multidimensional Sleep Health:…

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    News Source: www.sciencedaily.com

  • Stress, depression factor into link between insomnia, heavy drinking

    Stress, depression factor into link between insomnia, heavy drinking

    Insomnia and hazardous drinking are so closely intertwined that estimates suggest at least one-third, and as many as 91%, of people who have a hard time with sleep also misuse alcohol.

    A new study suggests that perceived stress and depression factor into the relationship between the two conditions — perhaps not a surprise. But because the relationship between insomnia and heavy drinking goes in both directions, the influence of stress or depression depends on which condition came first, the…

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    News Source: www.sciencedaily.com

  • New tool for cutting DNA: Promising prospects for biotechnology

    New tool for cutting DNA: Promising prospects for biotechnology

    An INRS team discovers a new family of enzymes capable of inducing targeted cuts in single-stranded DNA.

    A few years ago, the advent of technology known as CRISPR was a major breakthrough in the scientific world. Developed from a derivative of the immune system of bacteria, CRISPR enables double strands of nucleotides in deoxyribonucleic acid (DNA) to be cut. This makes it possible to specifically modify a targeted gene in plant, animal and human cells. Ultimately, CRISPR became a preferred…

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    News Source: www.sciencedaily.com

  • Combination of drugs could prevent thousands of heart attacks

    Combination of drugs could prevent thousands of heart attacks

    Patients who receive an add-on medication soon after a heart attack have a significantly better prognosis than those who receive it later, or not all.

    This is according to a new study from researchers at Lund University in Sweden and Imperial College London. The findings suggest that treating patients earlier with a combination of statins and the cholesterol-lowering drug ezetimibe could prevent thousands of new heart attacks over a decade.

    Cardiovascular disease is by far the most common…

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    News Source: www.sciencedaily.com

  • Recently discovered immune cell type is key to understanding food allergies

    Recently discovered immune cell type is key to understanding food allergies

    The immune system must be able to quickly attack invaders like viruses, while also ignoring harmless stimuli, or allergies can result. Immune cells are known to ignore or “tolerate” molecules found on the body’s own healthy cells, for instance, as well as nonthreatening substances from outside the body like food. How the system achieves the latter has been unclear.

    Now, a new study led by researchers at NYU Langone Health has revealed that a special group of cells in the intestines tamp down…

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    News Source: www.sciencedaily.com

  • A mysterious pathogen: Oropouche virus more common in Latin America than previously thought

    A mysterious pathogen: Oropouche virus more common in Latin America than previously thought

    Like the dengue and Zika viruses, Oropouche virus causes a febrile illness. There are recent indications that infections during pregnancy can cause damage to unborn babies. Researchers at Charité — Universitätsmedizin Berlin have now determined that the virus is much more widespread in Latin America than previously assumed. Their study, published in The Lancet Infectious Diseases, also suggests that climatic conditions have a significant influence on the virus’s spread.

    Oropouche virus…

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    News Source: www.sciencedaily.com

  • Popular CT scans could account for 5% of all cancer cases a year, study suggests

    Popular CT scans could account for 5% of all cancer cases a year, study suggests

    Radiation from imaging could lead to lung, breast and other future cancers, with 10-fold increased risk for babies.

    CT scans may account for 5% of all cancers annually, according to a new study out of UC San Francisco that cautions against overusing and overdosing CTs.

    The danger is greatest for infants, followed by children and adolescents. But adults also are at risk, since they are the most likely to get scans.

    Nearly 103,000 cancers are predicted to result from the 93 million CTs that…

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    News Source: www.sciencedaily.com

  • Study sheds light on how inherited cancer mutations drive tumor growth

    Study sheds light on how inherited cancer mutations drive tumor growth

    Most cancer genome studies have focused on mutations in the tumor itself and how such gene variants allow a tumor to grow unchecked. A new study, led by researchers at Washington University School of Medicine in St. Louis, takes a deep dive into inherited cancer mutations measured in a healthy blood sample and reports how those mutations might take a toll on the body’s cells starting at birth, perhaps predisposing a person to develop cancers at various stages of life.

    The authors analyzed…

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    News Source: www.sciencedaily.com

  • Cholesterol Levels Associated with Dementia

    Cholesterol Levels Associated with Dementia

    A study published in the British Medical Journal investigated the relationship between baseline low-density lipoprotein cholesterol (LDL-C) levels and the risk of developing dementia. The findings reveal a significant association, indicating that lower LDL-C levels (<70 mg/dL or 1.8 mmol/L and <55 mg/dL or 1.4 mmol/L) are linked to a reduced incidence of all-cause dementia and Alzheimer’s disease-related dementia (ADRD) compared to higher LDL-C levels…

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    News Source: www.labroots.com