Category: 4. Health

  • How cells repair their power plants

    How cells repair their power plants

    Damage to the genetic material of mitochondria — the mitochondrial DNA or mtDNA for short — can lead to diseases such as Parkinson’s, Alzheimer’s, amyotrophic lateral sclerosis (ALS), cardiovascular diseases and type 2 diabetes. Such damage also speeds up the ageing process. However, the cells are normally capable of identifying such damage and reacting.

    Scientists from University Hospital Düsseldorf and HHU have — in collaboration with the University of Cologne and the Center for…

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    News Source: www.sciencedaily.com

  • Novel genomic screening tool enables precision reverse-engineering of genetic programming in cells

    Novel genomic screening tool enables precision reverse-engineering of genetic programming in cells

    Collaborative research led by investigators at Dana-Farber/Boston Children’s Cancer and Blood Disorders Center defines a novel approach to understanding how certain proteins called transcription factors determine which genetic programs will drive cell growth and maturation. The method, called “Perturb-multiome,” uses CRISPR to knock out the function of individual transcription factors across many blood cells at once.

    The researchers then perform single-cell analyses on each cell to measure…

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    News Source: www.sciencedaily.com

  • Trump Administration Takes Aim At Trans Health And Identity

    Trump Administration Takes Aim At Trans Health And Identity

    In his State of the Union Address last month, President Trump told Congress that the Department of Government Efficiency had uncovered $8 million dollars allocated by the federal government to “make mice transgender.” There is of course no such thing as a transgender mouse. But there…

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    News Source: www.forbes.com

  • How U.S. public health cuts could raise risks of infectious diseases

    How U.S. public health cuts could raise risks of infectious diseases

    At 6 a.m. on March 25, Philip Huang, director of the Dallas County Health and Human Services department, got a devastating email. Millions of dollars in federal grants that the health agency had were suddenly gone.

    The U.S. Department of Health and Human Services had just rescinded about $12 billion from thousands of state and local health agencies, including Huang’s.

    Some of that money was part of a COVID-19 recovery program that health departments were using to beef up…

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    News Source: www.sciencenews.org

  • Signs identified that precede sudden arrhythmic death syndrome in young people

    Signs identified that precede sudden arrhythmic death syndrome in young people

    Recognising and detecting the signs that commonly precede sudden arrhythmic death syndrome (SADS) may help to prevent premature deaths, according to research presented today at ESC Preventive Cardiology 2025, a scientific congress of the European Society of Cardiology (ESC).

    “SADS has not been well evaluated despite being one of the most common underlying causes of sudden cardiac death in young people, including young athletes,” said study author Dr. Matilda Frisk Torell of Sahlgrenska…

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    News Source: www.sciencedaily.com

  • A Leap in viral research: More sensitive viral RNA detection

    A Leap in viral research: More sensitive viral RNA detection

    In a significant advancement, researchers from the Nanoscience Center (NSC) at the University of Jyväskylä, Finland, have unveiled innovative, label-free ratiometric fluorosensor designed for the selective and sensitive detection of enteroviral RNA. The research promises to deliver even more advanced and effective detection methods, reinforcing the importance of interdisciplinary collaboration in addressing global health challenges.

    Viruses pose a severe threat to global health, as…

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    News Source: www.sciencedaily.com

  • Molecular stool test could improve detection of tuberculosis in adults with HIV

    Molecular stool test could improve detection of tuberculosis in adults with HIV

    The Xpert MTB/Ultra molecular diagnostic test for stool samples, until now recommended only for children, could be established as an additional test for diagnosing tuberculosis in adults living with HIV. This is the main conclusion of the Stool4TB Alliance study, led by the Barcelona Institute for Global Health (ISGlobal), an institution supported by the “la Caixa” Foundation, in collaboration with the Manhiça Health Research Centre (CISM), the Research Center Borstel, the Makerere…

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    News Source: www.sciencedaily.com

  • NK cells complexed with bispecific antibody yield high response rates in patients with lymphoma

    NK cells complexed with bispecific antibody yield high response rates in patients with lymphoma

    A novel cell therapy approach using cord blood-derived natural killer (NK) cells pre-complexed with AFM13, or acimtamig, a CD30/CD16A bispecific antibody, was safe and generated strong response rates for patients with refractory CD30-positive lymphomas, according to a new study from The University of Texas MD Anderson Cancer Center.

    Results from the Phase I trial, published today in Nature Medicine, demonstrated an overall response rate of 92.9% and a complete response of 66.7% in 42 heavily…

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    News Source: www.sciencedaily.com

  • Artificial intelligence has potential to aid physician decisions during virtual urgent care

    Artificial intelligence has potential to aid physician decisions during virtual urgent care

    Do physicians or artificial intelligence (AI) offer better treatment recommendations for patients examined through a virtual urgent care setting? A new Cedars-Sinai study shows physicians and AI models have distinct strengths.

    The late-breaking study presented at the American College of Physicians Internal Medicine Meeting and published simultaneously in the Annals of Internal Medicine compared initial AI treatment recommendations to final recommendations of physicians who had access to the…

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    News Source: www.sciencedaily.com

  • How a small number of mutations can fuel outbreaks of western equine encephalitis virus

    How a small number of mutations can fuel outbreaks of western equine encephalitis virus

    New research shows how small shifts in the molecular makeup of a virus can profoundly alter its fate. These shifts could turn a deadly pathogen into a harmless bug or supercharge a relatively benign virus, influencing its ability to infect humans and cause dangerous outbreaks.

    This is the latest finding in a series of studies led by Jonathan Abraham, associate professor of microbiology in the Blavatnik Institute at Harvard Medical School, and his team that aim to understand the risk of…

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    News Source: www.sciencedaily.com