Category: 4. Health

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News Source: www.nature.com

  • Anti-progestin therapy targets hallmarks of breast cancer risk

    Anti-progestin therapy targets hallmarks of breast cancer risk

    The BC-APPS1 study

    The BC-APPS1 was a single-arm, single-centre phase II study registered under the name ‘a pilot prevention study of the effects of the anti-progestin ulipristal acetate (UA) on surrogate markers of breast cancer risk’…

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    News Source: www.nature.com

  • Synthetic α-synuclein fibrils replicate in mice causing MSA-like pathology

    Synthetic α-synuclein fibrils replicate in mice causing MSA-like pathology

    aSyn expression

    Escherichia coli strain BL21(DE3) was transformed with pT7-7 aSyn WT vector43 from Addgene, (plasmid 36046) and plated onto a Luria broth (LB) agar plate containing ampicillin (100 μg ml−1) and 1 g l−1 glucose. A…

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    News Source: www.nature.com

  • Just a moment…

    Just a moment…

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    News Source: medicalxpress.com

  • Just a moment…

    Just a moment…

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    News Source: medicalxpress.com

  • Targeting FSP1 triggers ferroptosis in lung cancer

    Targeting FSP1 triggers ferroptosis in lung cancer

    Cell lines

    KP LUAD cell lines were obtained from the laboratory of T. Jacks. KP, Fsp1KO cell lines were generated by transient transfection of PX458 (Addgene #48138) expressing an sgRNA targeting Fsp1. Single GFP-positive clones were selected and…

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    News Source: www.nature.com

  • Assessing phylogenetic confidence at pandemic scales

    Assessing phylogenetic confidence at pandemic scales

    SPRTA and aBayes

    Given an estimated rooted phylogenetic tree T and data D in the form of a multiple sequence alignment, our aim is to assign confidence scores to branches b of T.

    We take inspiration from the approximate Bayes (aBayes) approach17….

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    News Source: www.nature.com