Category: 4. Health

Lifestyle diseases such as cardiovascular diseases, diabetes, and chronic…

More than 12.4 million people worldwide suffer from the dominant form of the condition. Now, Rutgers University geneticists have uncovered fresh details of how the disease progresses — findings that could open the door to new therapies.

In a study published in Nature Communications, Inna Nikonorova, a…

The researchers, whose study is published in Pharmacological Research, identified the smallest part of a peptide (small protein) called PEPITEM, which occurs naturally in the body and regulates inflammation.

The study also showed that both PEPITEM and the three amino acid (tripeptide) sequence delivered a significant reduction in the…

Drugs that act on GPCRs, or G protein-coupled receptors, include more than 400 medications approved by the U.S. Food and Drug Administration (FDA) for treatment of many common conditions such as…

The research team, led by Michigan Medicine, examined the cognitive abilities of nearly 30,000 adults over time, comparing those who did and did not develop heart failure.

The researchers found heart failure is associated with a significant decrease in cognition at the time of diagnosis.

Global cognition and executive functioning also declined…

Immune cells are generated to keep our bodies healthy. To combat disease, our bodies initiate two separate waves of immunity. The first wave, known as innate immunity, is a generalizable response that tries to inhibit pathogens and stop disease progression. The second wave, known as adaptive immunity, is more specific and includes T and B cells. Both cell types generate a response that directly targets the invading pathogen. T cells are a specialized…

Immunotherapy has revolutionized the way physicians treat patients with cancer. This form of cancer treatment aims to direct the immune system toward the rapidly growing tumor. As cancer progresses, tumor cells secrete different proteins and molecules to suppress the body’s immune system. Various mechanisms are responsible for doing this, including surface proteins on cancer that inactivate specific immune cells, known as T cells. Many cells are…

President Donald Trump acted with restraint in his New Liberation Day tariffs, when he deferred imposing tariffs on pharmaceutical products from China, India and Europe. But, so long as these tariffs are being considered, their potential threat to the pharmaceutical industry and the people it serves remains.

These are difficult times for drug discovery and manufacturing. John Crowley the CEO of the Biotechnology…