Category: 4. Health

  • Drug combination reduces breast cancer risk and improves metabolic health in rats

    Drug combination reduces breast cancer risk and improves metabolic health in rats

    Approximately 25% of women in the United States between ages 45 and 60 are at high risk for breast cancer and should consider preventative medication, such as the commonly prescribed drug tamoxifen.

    Unfortunately, tamoxifen can cause side effects, including an increased risk for type 2 diabetes in women with excess body weight.

    In a study published in JCI Insight, researchers investigated the combined effects of bazedoxifene and conjugated estrogens in rat models as an alternative to…

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    News Source: www.sciencedaily.com

  • Low iron could cause brain fog during menopause transition

    Low iron could cause brain fog during menopause transition

    New research from the University of Oklahoma sheds light on an understudied area of science: iron levels in the blood and their relationship to cognitive performance in women transitioning into menopause. The findings are good news for women experiencing brain fog and other symptoms.

    Published in the journal Nutrients, the study suggests that when women have adequate levels of iron in their blood during the menopausal transition, they perform better on cognitive tasks. Moreover, sufficient…

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    News Source: www.sciencedaily.com

  • Natural killer cells remember and effectively target ovarian cancer

    Natural killer cells remember and effectively target ovarian cancer

    Researchers at Karolinska Institutet have uncovered a unique ability of a special subtype of natural killer cells in the immune system, called adaptive NK cells, to remember ovarian tumours and effectively attack them. The discovery, published in Cancer Immunology Research, could pave the way for new, more powerful immunotherapies for difficult-to-treat cancers.

    NK cells, or natural killer cells, are white blood cells that play a central role in the body’s defence against viral infections…

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    News Source: www.sciencedaily.com

  • United States sees disproportionate increase in body mass index rates of more than 60

    United States sees disproportionate increase in body mass index rates of more than 60

    In the past 20 years, the average rate of obesity among adults in the United States has risen by approximately 30 percent, but the rate of those with the most severe forms of obesity, or those with a body mass index, or BMI, of more than 60 kg/m2, increased by 210 percent. In a recently published research letter in the medical journal The Lancet: Diabetes & Endocrinology, researchers from Pennington Biomedical analyzed national health data from 2001 through 2023, and discovered the alarming…

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    News Source: www.sciencedaily.com

  • Gene circuits enable more precise control of gene therapy

    Gene circuits enable more precise control of gene therapy

    Many diseases are caused by a missing or defective copy of a single gene. For decades, scientists have been working on gene therapy treatments that could cure such diseases by delivering a new copy of the missing genes to the affected cells.

    Despite those efforts, very few gene therapy treatments have been approved by the FDA. One of the challenges to developing these treatments has been achieving control over how much the new gene is expressed in cells — too little and it won’t succeed,…

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    News Source: www.sciencedaily.com

  • Left or right arm? New research reveals why vaccination site matters for immune response

    Left or right arm? New research reveals why vaccination site matters for immune response

    Sydney scientists have revealed why receiving a booster vaccine in the same arm as your first dose can generate a more effective immune response more quickly. The study, led by the Garvan Institute of Medical Research and the Kirby Institute at UNSW Sydney and published in the journal Cell, offers new insight that could help improve future vaccination strategies.

    The researchers found that when a vaccine is administered, specialised immune cells called macrophages became ‘primed’ inside…

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    News Source: www.sciencedaily.com

  • Bacteria’s mysterious viruses can fan flames of antibiotic damage

    Bacteria’s mysterious viruses can fan flames of antibiotic damage

    Your gut microbiome teems with bacteria-eating viruses that have longed baffled scientists. Using a new mouse model that can eliminate and revive these virus communities, Virginia Tech biologists discovered that the viruses can exacerbate collateral damage from antibiotics.

    Some things just go together in your belly: peanut butter and jelly, salt and pepper, bacteria and bacteria-eating viruses.

    For the bacterial species that inhabit your gut, there’s a frenzy of viruses called…

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    News Source: www.sciencedaily.com

  • Influenza virus hacks cell’s internal system

    Influenza virus hacks cell’s internal system

    The influenza virus manipulates the body’s gene regulation system to accelerate its own spread, according to researchers at the University of Gothenburg. Their study also shows that an already approved drug could help strengthen immune defenses — though its effect in humans remains to be confirmed.

    The study, published in the journal Nucleic Acids Research, concerns a previously unknown strategy used by the influenza A virus to take over the body’s own systems. The study shows that the…

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    News Source: www.sciencedaily.com

  • Urine test could reveal early prostate cancer

    Urine test could reveal early prostate cancer

    A newly published study involving researchers from Karolinska Institutet indicates that prostate cancer can be diagnosed at an early stage through a simple urine sample. With the aid of AI and extensive analyses of gene activity in tumours, they have identified new biomarkers of high diagnostic precision.

    Prostate cancer is one of the most common causes of male death globally. One of the main diagnostic hurdles is the lack of exact biomarkers able to identify the presence of an early…

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    News Source: www.sciencedaily.com

  • Data collection changes key to understanding maternal mortality trends in the US, new study shows

    Data collection changes key to understanding maternal mortality trends in the US, new study shows

    A new study led by researchers at the University of Oxford, published today (28 April) in JAMA Pediatrics, offers fresh insight into trends in maternal mortality in the United States. For the first time, the study disentangles genuine changes in health outcomes from shifts caused by how deaths are recorded. Nevertheless, the study confirms the devastating impact of the COVID-19 pandemic on maternal death rates for women of all racial and ethnic groups.

    The study, based on data from 2000 to…

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    News Source: www.sciencedaily.com