Category: 4. Health

  • Increasing physical activity in middle age may protect against Alzheimer’s disease

    Increasing physical activity in middle age may protect against Alzheimer’s disease

    An increase in physical activity between the ages of 45 and 65 could help prevent Alzheimer’s disease, while inactivity may be detrimental to brain health. This is the main conclusion of a scientific paper published in Alzheimer’s & Dementia, which highlights the need to promote physical activity among middle-aged adults. The study is the result of a collaboration between the Barcelona Institute for Global Health (ISGlobal), a center promoted by the “la Caixa” Foundation, and the…

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    News Source: www.sciencedaily.com

  • New technology facilitates delivery of advanced medicines

    New technology facilitates delivery of advanced medicines

    Researchers at Karolinska Institutet in Sweden have developed a technique that enables efficient delivery of therapeutic proteins and RNA to cells. The method, presented in Nature Communications, shows promising results in animal studies to deliver gene editors and protein therapeutics.

    The method is based on so-called extracellular vesicles (EVs), tiny bubbles that are naturally secreted by cells and can transport biologically active molecules between cells. Researchers have now succeeded…

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    News Source: www.sciencedaily.com

  • New AI technique can uncover antiviral compounds using limited data

    New AI technique can uncover antiviral compounds using limited data

    Artificial intelligence algorithms have now been combined with traditional laboratory methods to uncover promising drug leads against human enterovirus 71 (EV71), the pathogen behind most cases of hand, foot and mouth disease. The study, published today in Cell Reports Physical Science by researchers at the Perelman School of Medicine at the University of Pennsylvania, showed that reliable antiviral predictions can be made even when only a modest amount of experimental data are available.

    AI…

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    News Source: www.sciencedaily.com

  • A virtual reality game integrating smell to fight cognitive decline

    A virtual reality game integrating smell to fight cognitive decline

    As the global population ages, supporting older adults in maintaining their cognitive and memory functions has become a pressing concern. The United Nations estimates that by the 2070s, there will be over 2.2 billion people aged 65 or older, surpassing the global number of children under 18. This demographic shift is especially pronounced in Japan, the fastest-aging country, where 28.7% of the population is 65 or older.

    One promising strategy to counter cognitive decline is through olfactory…

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    News Source: www.sciencedaily.com

  • Mechanism by which the brain weighs positive vs. negative social experience is revealed

    Mechanism by which the brain weighs positive vs. negative social experience is revealed

    Mount Sinai researchers have identified for the first time the neural mechanisms in the brain that regulate both positive and negative impressions of a social encounter, as well as how an imbalance between the two could lead to common neuropsychiatric disorders like autism spectrum disorder (ASD) and schizophrenia. The study, published April 30 in Nature, also describes how activating a serotonin receptor in the brain of a mouse model ofASD restored positive emotional value (also known as…

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    News Source: www.sciencedaily.com

  • In two decades increasing urban vegetation could have saved over 1.1 million lives

    In two decades increasing urban vegetation could have saved over 1.1 million lives

    Increasing urban vegetation by 30% could save over one-third of all heat related deaths, saving up to 1.16 million lives globally from 2000 to 2019 according to a 20-year modelling study of the impact of increasing greenness in more than 11,000 urban areas.

    The study, led by Monash University Professor Yuming Guo and published in The Lancet Planetary Health, showed that increasing vegetation levels by 10%, 20%, and 30% would:

    decrease the global population-weighted warm-season mean…

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    News Source: www.sciencedaily.com

  • Study links childhood trauma to increased substance use and unexpected effects on heart rate and blood pressure in adolescents

    Study links childhood trauma to increased substance use and unexpected effects on heart rate and blood pressure in adolescents

    A new study published in the Journal of Child Psychology and Psychiatry reveals that childhood trauma significantly increases the likelihood of engaging in risky behaviours, including harmful alcohol consumption, smoking and illicit drug use, by the age of 18. The research is led by the University of Bath and the University of São Paulo.

    The study analysed data from the 2004 Pelotas Birth Cohort in Brazil, which has tracked over 4,000 children living in southern Brazil from birth to age 18….

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    News Source: www.sciencedaily.com

  • Depression and other mental health conditions linked with immune response, study finds

    Depression and other mental health conditions linked with immune response, study finds

    Depression, schizophrenia and other mental health conditions affect 1 in 4 people in their lifetime, but mechanisms underlying these conditions are poorly understood. New research led by researchers at the University of Bristol has linked the body’s immune response with schizophrenia, Alzheimer’s disease, depression, and bipolar disorder. The study demonstrates mental health conditions might be affected by the whole body as well as changes in the brain. The findings could pave the way for…

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    News Source: www.sciencedaily.com

  • Protein sources change the gut microbiome — some drastically

    Protein sources change the gut microbiome — some drastically

    A new study by researchers from North Carolina State University shows that protein sources in an animal’s diet can have major effects on both the population and function of the microscopic life within their gut. These microorganisms, known as the gut microbiome, can impact various aspects of our health. The findings could help lead to a better understanding of how to prevent and treat gastrointestinal diseases currently affecting the quality of life of millions of people globally.

    “There’s…

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    News Source: www.sciencedaily.com

  • Researchers find that increase of ‘CLU’ protein promotes brain resilience and could provide protection from Alzheimer’s disease

    Researchers find that increase of ‘CLU’ protein promotes brain resilience and could provide protection from Alzheimer’s disease

    Recently approved Alzheimer’s drugs offer a step forward for treating the disease, but new therapeutic strategies are needed to complement them and provide personalized therapeutic approaches. Mass General Brigham researchers have identified a potential strategy to protect against Alzheimer’s disease by increasing the clusterin protein (CLU). Their results, published in Neuron, uncover the mechanism of how increased CLU protects the brain from amyloid plaques and loss of synapses, key…

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    News Source: www.sciencedaily.com