Category: 4. Health

  • Study finds one protein that mitigates Huntington’s disease, and one that exacerbates it

    Study finds one protein that mitigates Huntington’s disease, and one that exacerbates it

    A decade ago, University at Buffalo researchers shed some light on an enduring neuroscience mystery: How exactly does a mutated huntingtin protein (HTT) cause Huntington’s disease?

    They found that HTT is something like a traffic controller inside neurons, moving different cargo along neuronal highways called axons in concert with other proteins key for cellular function and survival. Reduce the amount of non-mutant HTT and you’ll create the neurological equivalent of traffic jams and…

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    News Source: www.sciencedaily.com

  • A long and ongoing look at the secrets of human longevity and healthy aging

    A long and ongoing look at the secrets of human longevity and healthy aging

    It’s notable when a scientific study reaches the decade mark, but when the topic is the healthy aging of people who have lived 10 times as long, it just means there’s still a lot more to learn.

    This month, researchers participating in the Cilento Initiative on Aging Outcomes or CIAO study will gather in Acciaroli (Pollica-Cilento) Salerno, Italy to review a decade of work and plan their next steps. Launched in 2016, the CIAO study seeks to identify key factors (biological, psychological and…

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    News Source: www.sciencedaily.com

  • Neighborhood stress may impact kids’ brains — and increase depression risk

    Neighborhood stress may impact kids’ brains — and increase depression risk

    Children who grow up in disadvantaged neighborhoods — areas with higher levels of crime and deprivation, and lower access to community resources — are at risk of developing depression and new research led by faculty at Binghamton University, State University of New York, may help to explain why.

    Psychologists at Binghamton found that the brains of children from areas containing higher levels of deprivation show less response to reward and loss, but only if they were already at risk for…

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    News Source: www.sciencedaily.com

  • Structural barriers may prevent cancer care for people living with HIV

    Structural barriers may prevent cancer care for people living with HIV

    People living with HIV are less likely to receive potentially lifesaving cancer treatment if they live in communities with lower income levels and educational attainment, according to a new national study led by researchers from Moffitt Cancer Center.

    In the study, published in Cancer, researchers looked at cancer treatment records for more than 31,000 adults with HIV who were diagnosed with one of 14 common cancers between 2004 and 2020. They found that 16.5% of them did not receive the…

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    News Source: www.sciencedaily.com

  • Topical gel relieved ear infections in animals after just one dose

    Topical gel relieved ear infections in animals after just one dose

    Ear infections are a common and painful occurrence in infants and toddlers. Oral antibiotics are often prescribed for a week to treat the condition, but these drugs can trigger side effects that disrupt treatment, which can lead to infection recurrence and antibiotic resistance. Now, researchers in ACS Nano report a topical antibiotic gel that, applied once, cured middle ear infection within 24 hours in chinchillas.

    “I often receive emails from parents asking when our formulation will be…

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    News Source: www.sciencedaily.com

  • Certain traits in romantic partners can amplify the impact of a person’s genetic risk for alcohol problems

    Certain traits in romantic partners can amplify the impact of a person’s genetic risk for alcohol problems

    A study led by Virginia Commonwealth University and Rutgers University has revealed new insights into how romantic partners can influence a person’s genetic predisposition to unhealthy alcohol use. The research team specifically found that the substance use habits, personality traits and mental health status of long-term partners can enhance or diminish the impact of a person’s genetic risk for binge drinking. The findings could help reshape strategies for couples therapy and couple-based…

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    News Source: www.sciencedaily.com

  • Biological ‘clocks’ key to muscle health and accelerated aging in shift workers

    Biological ‘clocks’ key to muscle health and accelerated aging in shift workers

    Muscle cells contain their own circadian clocks and disrupting them with shift work can have a profound impact on ageing, according to new research.

    A study published today in Proceedings of the National Academy of Sciences (PNAS) contributes to the growing evidence of the damage shift work has on health.

    The King’s College London team revealed how muscle cells have an intrinsic timekeeping mechanism that regulates protein turnover, modulating muscle growth and function. At night, the muscle…

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    News Source: www.sciencedaily.com

  • New molecular label could lead to simpler, faster tuberculosis tests

    New molecular label could lead to simpler, faster tuberculosis tests

    Tuberculosis, the world’s deadliest infectious disease, is estimated to infect around 10 million people each year, and kills more than 1 million annually. Once established in the lungs, the bacteria’s thick cell wall helps it to fight off the host immune system.

    Much of that cell wall is made from complex sugar molecules known as glycans, but it’s not well-understood how those glycans help to defend the bacteria. One reason for that is that there hasn’t been an easy way to label them inside…

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    News Source: www.sciencedaily.com

  • PTSD patients show long-term benefits with vagus nerve stimulation

    PTSD patients show long-term benefits with vagus nerve stimulation

    In a first-of-its-kind clinical study, scientists at The University of Texas at Dallas and Baylor University Medical Center showed that patients with treatment-resistant PTSD were symptom-free up to six months after completing traditional therapy paired with vagus nerve stimulation (VNS).

    The results of the nine-patient Phase 1 trial, conducted by scientists from UT Dallas’ Texas Biomedical Device Center (TxBDC) in collaboration with researchers from the Baylor Scott & White Research…

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    News Source: www.sciencedaily.com

  • What It Means For Patients, Payers, And Pharma

    What It Means For Patients, Payers, And Pharma

    CVS Health last Thursday announced that its pharmacy benefit manager division will drop Eli Lilly’s Zepbound from its preferred formulary list starting July 1, 2025. Instead, CVS will prioritize coverage of Wegovy, a competing GLP-1 medication produced by Novo Nordisk.

    The move is another skirmish in a broader set of…

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    News Source: www.forbes.com