Category: 4. Health

  • Common antidepressants could help the immune system fight cancer

    Common antidepressants could help the immune system fight cancer

    A widely used antidepressant drug could help the immune system fight cancer, according to a new UCLA research study.

    Selective serotonin reuptake inhibitors, or SSRIs, significantly enhanced the ability of T cells to fight cancer and suppressed tumor growth across a range of cancer types in both mouse and human tumor models, the study, published in Cell, found.

    “It turns out SSRIs don’t just make our brains happier; they also make our T cells happier — even while they’re fighting tumors,”…

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    News Source: www.sciencedaily.com

  • Newfound mechanism rewires cellular energy processing for drastic weight loss

    Newfound mechanism rewires cellular energy processing for drastic weight loss

    Mice genetically engineered to lack the ability to make the amino acid cysteine, and fed a cysteine-free diet, lost 30 percent of their body weight in just one week, a new study shows.

    Published online May 21 in Nature, the work found that cysteine depletion disrupts the normal metabolic pathways used by mammalian cells to convert food into energy, forcing the animals to rapidly burn fat stores in a futile attempt to meet energy demands.

    Led by researchers at NYU Grossman School of Medicine,…

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    News Source: www.sciencedaily.com

  • Live view: Stress-induced changes in generations of cancer cells

    Live view: Stress-induced changes in generations of cancer cells

    Cancer cells respond to stress with greater diversity. Drugs that affect DNA replication, or radiation that causes direct DNA damage, lead to increasingly diverse offspring over multiple cell generations. This increases the tumor’s genetic complexity and facilitates the development of resistance to therapy. UZH researchers have now investigated the emergence of cellular diversity in real time.

    Cells are the smallest units of life. But even within the same tissue or organ, they are not all…

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    News Source: www.sciencedaily.com

  • Clinical trial shows improvements for spinal cord injuries

    Clinical trial shows improvements for spinal cord injuries

    In a new clinical study, researchers from the Texas Biomedical Device Center (TxBDC) at The University of Texas at Dallas demonstrated unprecedented rates of recovery for spinal cord injuries.

    In this study, published in the journal Nature on May 21, individuals with incomplete spinal cord injury safely received a combination of stimulation of a nerve in the neck with progressive, individualized rehabilitation. This approach, called closed-loop vagus nerve stimulation (CLV), produced…

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    News Source: www.sciencedaily.com

  • Scientists design gene delivery systems for cells in the brain and spinal cord

    Scientists design gene delivery systems for cells in the brain and spinal cord

    Research teams funded by the National Institutes of Health (NIH) have created a versatile set of gene delivery systems that can reach different neural cell types in the human brain and spinal cord with exceptional accuracy. These delivery systems are a significant step toward future precise gene therapy to the brain that could safely control errant brain activity with high precision. In contrast, current therapies for brain disorders mostly treat only symptoms.

    The new delivery systems carry…

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    News Source: www.sciencedaily.com

  • Scientists reveal how energy is delivered into the cells major ‘shipping port’

    Scientists reveal how energy is delivered into the cells major ‘shipping port’

    A team of scientists has answered a long-standing question in cell biology, uncovering how the cell’s main energy currency, ATP, is transported into the endoplasmic reticulum (ER). Disrupted energy transport could affect diseases such as type 2 diabetes, cancer, and neurodegenerative disorders. The study, published in Nature, confirms that the transporter protein SLC35B1 is the key gateway for ATP entry into the ER.

    The research, led by David Drew, Professor of biochemistry at Stockholm…

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    News Source: www.sciencedaily.com

  • Hand2: positional code that allows axolotls to regrow limbs found

    Hand2: positional code that allows axolotls to regrow limbs found

    With its fascinating ability to regrow entire limbs and internal organs, the Mexican axolotl is the ideal model for studying regeneration. Scientists from the lab of Elly Tanaka at IMBA now found a factor that tells cells which part of the arm to regenerate — and used it to reprogram the identity of cells as they develop. This breakthrough for the regeneration research field has implications for tissue engineering, including in human tissues. The study was published in the journal Nature

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    News Source: www.sciencedaily.com

  • How Marvel’s Thunderbolts Film Gets Mental Health and Messaging Right

    How Marvel’s Thunderbolts Film Gets Mental Health and Messaging Right

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    News Source: www.forbes.com

  • FDA Will Limit Covid-19 Vaccines To Those Over 65 Or At High Risk

    FDA Will Limit Covid-19 Vaccines To Those Over 65 Or At High Risk

    In this week’s edition of InnovationRx, we look at the FDA’s new COVID-19 vaccine rules, Novartis’s acquisition strategy, Medtronic’s diabetes spinoff, Regeneron’s purchase of 23AndMe, and more. To get it in your inbox, subscribe here.

    On Tuesday, the FDA announced that it’s adopting a new regulatory framework for COVID-19 vaccines. Under this guidance, published in the New England Journal of Medicine, recommendations for booster shots will be limited to those 65 and older…

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    News Source: www.forbes.com

  • Scientists Reveal Cells That Have a Close Link to Allergies

    Scientists Reveal Cells That Have a Close Link to Allergies

    Scientists learned about a decade ago that when children were given peanuts in the first few months of life, their chances of developing a peanut allergy were lower compared to children who were not given any peanuts during that time of life. Researchers have now identified a cell type that could explain this finding; a class of immune cells called Thetis cells, which were first identified in 2022. Thetis cells seem to have a role in suppressing the…

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    News Source: www.labroots.com