Category: 4. Health

A single sperm donor who carries a rare cancer-causing genetic mutation has fathered at least 197 children across 14 countries in Europe, according to a collaborative investigation by 14…

Datasets

GWAS data

We downloaded the publicly available GWAS summary statistics and SNP heritability estimates for traits in the UKB from Ben Neale’s laboratory (see the URL section below). We focused on traits with SNP heritability estimates…

Animal experiments

All mouse experiments were performed in accordance with institutional guidelines for animal care and use established in the Principles of Laboratory Animal Care (directive 86/609/EEC). Animal work was only initiated upon…

Human specimens and organoid lines

Two terminal ileum tissues (donors H0514 and H0515-2) were obtained for immunofluorescent staining and flow cytometry analysis from Diakonessen Hospital Utrecht, with approval by the Medical Ethical Committee of…

Malaria remains a major public health concern, with many African nations being far from meeting their malaria elimination targets^4,5. Vector control methods including indoor residual spraying and long-lasting insecticide-treated bed nets have…