Category: 4. Health

  • Rapid growth of blood cancer driven by a single genetic ‘hit’

    Rapid growth of blood cancer driven by a single genetic ‘hit’

    A new study has unveiled when chronic myeloid leukaemia, a type of cancer that affects the blood and bone marrow, arises in life and how fast it grows. Researchers reveal explosive growth rates of cancerous cells years before diagnosis and variation in these rates of growth between patients. Such rapid growth rates had previously not been observed in most other cancers.

    Researchers from the Wellcome Sanger Institute and their collaborators used whole genome sequencing to study when BCR::ABL1

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    News Source: www.sciencedaily.com

  • Further translation of the language of the genome

    Further translation of the language of the genome

    New research has uncovered more about the complexity of human gene regulation by identifying certain sequences of proteins called transcription factors that bind to DNA and regulate the expression of human genes.

    Published today (9 April) in Nature, researchers from the Wellcome Sanger Institute, the University of Cambridge and their collaborators explored how DNA-guided transcription factors interact with each other.

    This research adds to the groundwork of understanding the complex language…

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    News Source: www.sciencedaily.com

  • Could LLMs help design our next medicines and materials?

    Could LLMs help design our next medicines and materials?

    The process of discovering molecules that have the properties needed to create new medicines and materials is cumbersome and expensive, consuming vast computational resources and months of human labor to narrow down the enormous space of potential candidates.

    Large language models (LLMs) like ChatGPT could streamline this process, but enabling an LLM to understand and reason about the atoms and bonds that form a molecule, the same way it does with words that form sentences, has presented a…

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    News Source: www.sciencedaily.com

  • What links cannabis use and psychosis? Researchers point to brain’s dopamine system

    What links cannabis use and psychosis? Researchers point to brain’s dopamine system

    A McGill University-led study found that people with cannabis use disorder (CUD) had elevated dopamine levels in a brain region associated with psychosis.

    “This could help explain why cannabis use increases the risk of hallucinations and delusions, key symptoms of schizophrenia and other psychotic disorders,” said first author Jessica Ahrens, a PhD student in McGill’s Integrated Program in Neuroscience.

    Dopamine is a neurotransmitter that helps regulate mood and motivation, and an excess is…

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    News Source: www.sciencedaily.com

  • Protein necessary for fruit fly fertility

    Protein necessary for fruit fly fertility

    The global birthrate has been in significant decline for decades. In the U.S., couples are deciding to have children later in life. A 2022 U.S. Census data analysis of Census Bureau and National Center for Health Statistics data, reveals that fertility rates for women age 20-24 declined by 43% during the period from 1990 to 2013. But the numbers of women age 35-39 giving birth increased by 67%, and for women between 40- 44 that increase was nearly 139%.

    Women who decide to have children in…

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    News Source: www.sciencedaily.com

  • Researchers identify precision medicine approach for preventing kidney failure

    Researchers identify precision medicine approach for preventing kidney failure

    New UCLA research conducted using mouse models and human genetic data has uncovered a critical factor that determines how much scarring occurs following kidney injury, leading scientists to identify a potential precision medicine approach to prevent chronic kidney disease progression.

    The study, published in Science Translational Medicine, highlights the role of type 5 collagen — a minor component of scar tissue — in kidney fibrosis, and shows how an experimental therapy could help prevent…

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    News Source: www.sciencedaily.com

  • More people now die at home after stroke than in medical facilities

    More people now die at home after stroke than in medical facilities

    A new analysis finds a significant uptick in the number of people dying at home due to ischemic stroke compared to inpatient medical facilities, and when not at home, individuals in rural communities and Black Americans were more likely to die in less specialized care environments.

    Additionally, the researchers found that after a steady 10-year decline, overall death rates from stroke are now rising.

    These findings, published in PLOS One by researchers at Georgetown University School of…

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    News Source: www.sciencedaily.com

  • Multi-virus wastewater surveillance shows promise at smaller, site-specific scales

    Multi-virus wastewater surveillance shows promise at smaller, site-specific scales

    In a new study, wastewater surveillance for multiple pathogens at five different sites identified local trends that were not captured in larger surveillance programs, and some sites used the data to inform efforts to prevent disease spread. Jay Bullen of Untap Health in London, U.K., Charlotte Hammer of the University of Cambridge and colleagues present these findings in the open-access journal PLOS Global Public Health.

    People with viral infections produce waste containing viral RNA that…

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    News Source: www.sciencedaily.com

  • Stroke deaths and their racial disparities increased over last 20 years

    Stroke deaths and their racial disparities increased over last 20 years

    Over the last two decades, ischemic stroke mortality rates in the U.S. have grown, with almost 3 in 10 deaths occurring at home, and increases particularly among racial minorities and rural residents. These growing disparities were among the findings of a new study publishing April 9, 2025, in the open-access journal PLOS One by Jason Lim of Georgetown University School of Medicine, U.S., and colleagues.

    Stroke remains the fifth leading cause of mortality in the United States. Understanding…

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    News Source: www.sciencedaily.com

  • Discovery reveals protein involved in Parkinson’s disease also drives skin cancer

    Discovery reveals protein involved in Parkinson’s disease also drives skin cancer

    A small protein involved in neurodegeneration leading to Parkinson’s disease also drives a type of skin cancer known as melanoma, new research led by Oregon Health & Science University finds.

    The study, published today in the journal Science Advances, suggests new avenues for drug development to reduce the risk of developing both Parkinson’s and skin cancer by targeting the alpha-synuclein protein, which appears to have a critical role in regulating cellular functions.

    “Developing drugs that…

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    News Source: www.sciencedaily.com