Category: 4. Health

  • Simple test could better predict your risk of heart disease

    Simple test could better predict your risk of heart disease

    For almost 60 years, measuring cholesterol levels in the blood has been the best way to identify individuals at high risk of cardiovascular disease. In a new study, led by Chalmers University of Technology in Sweden and Harvard University in the USA, researchers have shown comprehensively that a combination of two lipoprotein markers, measured in a simple blood test, can give more accurate information about individual risk of heart disease than the current blood cholesterol test, potentially…

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    News Source: www.sciencedaily.com

  • Viewing organs in 3D | ScienceDaily

    Viewing organs in 3D | ScienceDaily

    It is now possible to obtain three-dimensional, high-resolution images of enzyme activity in tissue samples or whole organs — thanks to probe molecules that anchor fluorescent dyes within tissue as they are activated by enzymes. The organ being mapped is made transparent by a clearing process. As a Japanese team reported in the journal Angewandte Chemie, this allowed for visualization of differences in aminopeptidase N activity and the effects of inhibitors in mouse kidneys.

    Enzymes play a…

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    News Source: www.sciencedaily.com

  • New AI model improves MS diagnostics

    New AI model improves MS diagnostics

    To provide the right treatment for MS, it is important to know when the disease changes from relapsing-remitting to secondary progressive, a transition that is currently recognised on average three years too late. Researchers at Uppsala University have now developed an AI model that can determine with 90 percent certainty which variant the patient has.

    Multiple sclerosis (MS) is a chronic, inflammatory disease of the central nervous system. In Sweden, there are approximately 22,000 people…

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    News Source: www.sciencedaily.com

  • Cell colonies under pressure: How growth can prevent motion

    Cell colonies under pressure: How growth can prevent motion

    The interaction between growth and the active migration of cells plays a crucial role in the spatial mixing of growing cell colonies. This connection was discovered by scientists from the Department of Living Matter Physics at the Max Planck Institute for Dynamics and Self-Organization (MPI-DS). Their results provide new approaches to understanding the dynamics of bacterial colonies and tumors.

    The ability to actively migrate is a fundamental property of living matter such as cells….

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    News Source: www.sciencedaily.com

  • Drug combination reduces breast cancer risk and improves metabolic health in rats

    Drug combination reduces breast cancer risk and improves metabolic health in rats

    Approximately 25% of women in the United States between ages 45 and 60 are at high risk for breast cancer and should consider preventative medication, such as the commonly prescribed drug tamoxifen.

    Unfortunately, tamoxifen can cause side effects, including an increased risk for type 2 diabetes in women with excess body weight.

    In a study published in JCI Insight, researchers investigated the combined effects of bazedoxifene and conjugated estrogens in rat models as an alternative to…

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    News Source: www.sciencedaily.com

  • Natural killer cells remember and effectively target ovarian cancer

    Natural killer cells remember and effectively target ovarian cancer

    Researchers at Karolinska Institutet have uncovered a unique ability of a special subtype of natural killer cells in the immune system, called adaptive NK cells, to remember ovarian tumours and effectively attack them. The discovery, published in Cancer Immunology Research, could pave the way for new, more powerful immunotherapies for difficult-to-treat cancers.

    NK cells, or natural killer cells, are white blood cells that play a central role in the body’s defence against viral infections…

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    News Source: www.sciencedaily.com

  • United States sees disproportionate increase in body mass index rates of more than 60

    United States sees disproportionate increase in body mass index rates of more than 60

    In the past 20 years, the average rate of obesity among adults in the United States has risen by approximately 30 percent, but the rate of those with the most severe forms of obesity, or those with a body mass index, or BMI, of more than 60 kg/m2, increased by 210 percent. In a recently published research letter in the medical journal The Lancet: Diabetes & Endocrinology, researchers from Pennington Biomedical analyzed national health data from 2001 through 2023, and discovered the alarming…

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    News Source: www.sciencedaily.com

  • Gene circuits enable more precise control of gene therapy

    Gene circuits enable more precise control of gene therapy

    Many diseases are caused by a missing or defective copy of a single gene. For decades, scientists have been working on gene therapy treatments that could cure such diseases by delivering a new copy of the missing genes to the affected cells.

    Despite those efforts, very few gene therapy treatments have been approved by the FDA. One of the challenges to developing these treatments has been achieving control over how much the new gene is expressed in cells — too little and it won’t succeed,…

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    News Source: www.sciencedaily.com

  • Left or right arm? New research reveals why vaccination site matters for immune response

    Left or right arm? New research reveals why vaccination site matters for immune response

    Sydney scientists have revealed why receiving a booster vaccine in the same arm as your first dose can generate a more effective immune response more quickly. The study, led by the Garvan Institute of Medical Research and the Kirby Institute at UNSW Sydney and published in the journal Cell, offers new insight that could help improve future vaccination strategies.

    The researchers found that when a vaccine is administered, specialised immune cells called macrophages became ‘primed’ inside…

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    News Source: www.sciencedaily.com

  • Bacteria’s mysterious viruses can fan flames of antibiotic damage

    Bacteria’s mysterious viruses can fan flames of antibiotic damage

    Your gut microbiome teems with bacteria-eating viruses that have longed baffled scientists. Using a new mouse model that can eliminate and revive these virus communities, Virginia Tech biologists discovered that the viruses can exacerbate collateral damage from antibiotics.

    Some things just go together in your belly: peanut butter and jelly, salt and pepper, bacteria and bacteria-eating viruses.

    For the bacterial species that inhabit your gut, there’s a frenzy of viruses called…

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    News Source: www.sciencedaily.com