Palestine

Category: 4. Health

  • Researchers find that increase of ‘CLU’ protein promotes brain resilience and could provide protection from Alzheimer’s disease

    Researchers find that increase of ‘CLU’ protein promotes brain resilience and could provide protection from Alzheimer’s disease

    Recently approved Alzheimer’s drugs offer a step forward for treating the disease, but new therapeutic strategies are needed to complement them and provide personalized therapeutic approaches. Mass General Brigham researchers have identified a potential strategy to protect against Alzheimer’s disease by increasing the clusterin protein (CLU). Their results, published in Neuron, uncover the mechanism of how increased CLU protects the brain from amyloid plaques and loss of synapses, key…

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    News Source: www.sciencedaily.com

  • Mechanism by which the brain weighs positive vs. negative social experience is revealed

    Mechanism by which the brain weighs positive vs. negative social experience is revealed

    Mount Sinai researchers have identified for the first time the neural mechanisms in the brain that regulate both positive and negative impressions of a social encounter, as well as how an imbalance between the two could lead to common neuropsychiatric disorders like autism spectrum disorder (ASD) and schizophrenia. The study, published April 30 in Nature, also describes how activating a serotonin receptor in the brain of a mouse model ofASD restored positive emotional value (also known as…

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    News Source: www.sciencedaily.com

  • Mindfulness therapy reduces opioid craving and addiction, study finds

    Mindfulness therapy reduces opioid craving and addiction, study finds

    Researchers from the University of California San Diego have found that Mindfulness-Oriented Recovery Enhancement (MORE) can help rewire the brain’s response to natural healthy pleasure, leading to improved mood, greater attention to positive experiences and reduced opioid cravings. The findings, published on April 30, 2025 in the Journal of the American Medical Association (JAMA), suggest that this evidence-based therapy may be a promising tool in the fight against opioid use disorder…

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    News Source: www.sciencedaily.com

  • Novel rat model paves the way to advance COPD-associated cor pulmonale research

    Novel rat model paves the way to advance COPD-associated cor pulmonale research

    Philadelphia, April 30, 2025 – Researchers have developed a novel rat model that closely replicates the pathological features and physiological changes associated with human chronic obstructive pulmonary disease (COPD)-associated cor pulmonale. This model exhibits key characteristics, including chronic lung inflammation, pulmonary hypertension, and right ventricular hypertrophy. The new study in The American Journal of Pathology, published by Elsevier, details the potential for the model…

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    News Source: www.sciencedaily.com

  • New model to study hypertension and aortic aneurysms developed

    New model to study hypertension and aortic aneurysms developed

    Oxidative stress can occur when our cells are exposed to harmful molecules called “reactive oxygen species” over time. These reactive oxygen species can damage cells and are found in important disease states, such as high blood pressure and aortic aneurysms. Aortic aneurysms are balloon-like swellings of the body’s largest artery and are often fatal when the aneurysm bursts.

    Investigators at Mass General Brigham have discovered a new pathway that may lead to a treatment for high blood…

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    News Source: www.sciencedaily.com

  • New drug shows promise for treating bronchiectasis

    New drug shows promise for treating bronchiectasis

    Results of a large, global clinical trial spanning five continents with over 1,700 patients with bronchiectasis, published this April in the New England Journal of Medicine, demonstrated benefits of an investigational, once-a-day pill called brensocatib as a therapy for the chronic lung condition.

    The clinical trial findings are important, as there are currently no FDA-approved medications for bronchiectasis, a chronic condition with persistent lung airway inflammation and infection….

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    News Source: www.sciencedaily.com

  • Bacterial villain behind Lake Erie’s ‘potent toxin’ unveiled

    Bacterial villain behind Lake Erie’s ‘potent toxin’ unveiled

    In the warm summertime waters of Lake Erie, cyanobacteria, or blue-green algae, can proliferate out of control, creating algal blooms that produce toxins at a rate that can harm wildlife and human health.

    Now, University of Michigan researchers have identified the organism responsible for producing the toxins: a type of cyanobacteria called Dolichospermum.

    Harmful algal blooms, or HABs, can be composed of different types of cyanobacteria, which can produce different types of toxins. Knowing…

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    News Source: www.sciencedaily.com

  • ‘Explainable’ AI cracks secret language of sticky proteins

    ‘Explainable’ AI cracks secret language of sticky proteins

    An AI tool has made a step forward in translating the language proteins use to dictate whether they form sticky clumps similar to those linked to Alzheimer’s Disease and around fifty other types of human disease. In a departure from typical “black-box” AI models, the new tool, CANYA, was designed to be able to explain its decisions, revealing the specific chemical patterns that drive or prevent harmful protein folding.

    The discovery, published today in the journal Science Advances, was…

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    News Source: www.sciencedaily.com

  • Machine learning brings new insights to cell’s role in addiction, relapse

    Machine learning brings new insights to cell’s role in addiction, relapse

    Object recognition software is used by law enforcement to help identify suspects, by self-driving cars to navigate roadways and by many consumers to unlock their cell phones or pay for their morning coffee.

    Now, researchers led by the University of Cincinnati’s Anna Kruyer and the University of Houston’s Demetrio Labate have applied object recognition technology to track changes in brain cell structure and provide new insights into how the brain responds to heroin use, withdrawal and…

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    News Source: www.sciencedaily.com

  • New ‘hidden in plain sight’ facial and eye biomarkers for tinnitus severity could unlock path to testing treatments

    New ‘hidden in plain sight’ facial and eye biomarkers for tinnitus severity could unlock path to testing treatments

    Researchers at Mass General Brigham have identified new biomarkers for tinnitus by measuring pupil dilation and subtle facial movements that correlate with the level of distress caused by the disorder. Published in Science Translational Medicine, the findings could lead to placebo-controlled treatment studies that have largely been not feasible due to lack of objective measures.

    “Imagine if cancer severity were determined by giving patients a questionnaire — this is the state of affairs for…

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    News Source: www.sciencedaily.com