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  • Developing software for easy estimation of 3D gene expression distribution

    Developing software for easy estimation of 3D gene expression distribution

    Understanding the 3D spatial distribution of gene expression — in which a gene is active or inactive within biological tissue — is essential for uncovering gene functions. One method for estimating this distribution is RNA tomography, involving preparing frozen tissue sections along three orthogonal axes, performing RNA sequencing (gene expression analysis) on each section, and superimposing the expression data to reconstruct a 3D gene expression map. However, processing this data requires…

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    News Source: www.sciencedaily.com

  • Revolutionizing protein modification: A new frontier in cancer research

    Revolutionizing protein modification: A new frontier in cancer research

    A research team led by Professor Seung Soo Oh and Dr. Hyesung Jo from the Department of Materials Science and Engineering at POSTECH (Pohang University of Science and Technology) has developed an innovative technique that enables precise modification of specific proteins within complex biological environments. Their pioneering work has been featured as a Supplementary Cover in the Journal of the American Chemical Society (JACS).

    Proteins are essential components of our bodies and play…

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    News Source: www.sciencedaily.com

  • Preclinical study: After heart attack, a boost in anti-inflammatory cells promoted healing

    Preclinical study: After heart attack, a boost in anti-inflammatory cells promoted healing

    A scientific technique that rapidly increases the body’s production of anti-inflammatory cells promoted healing from heart attacks in mice, according to a new study by investigators from the Smidt Heart Institute at Cedars-Sinai. Once adapted to treat humans, the technique could potentially be used to repair heart muscle damage after a heart attack and be applied to a variety of inflammatory disorders.

    The investigators’ findings were published in the peer-reviewed Journal of Clinical…

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    News Source: www.sciencedaily.com

  • Effects of multifunctional facility on daily walking time

    Effects of multifunctional facility on daily walking time

    Designing walkable neighborhoods has gained attention as a method to increase physical activity among urban populations. Moreover, highly walkable areas stimulate increased neighborhood retail sales, higher property values, and greater urban sustainability. However, only limited methods are available for improving walkability in the urban centers of highly motorized suburban cities. In the urban areas of suburban cities, increasing land-use diversity by opening a multifunctional facility is…

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    News Source: www.sciencedaily.com

  • mRNA-based COVID-19 vaccines train the ‘long-term memory’ of the immune system

    mRNA-based COVID-19 vaccines train the ‘long-term memory’ of the immune system

    Researchers at the University of Cologne and University Hospital Cologne have shown in their study that the novel mRNA-based COVID-19 vaccines not only induce acquired immune responses such as antibody production, but also cause persistent epigenetic changes in innate immune cells. The study ‘Persistent epigenetic memory of SARS-CoV-2 mRNA vaccination in monocyte-derived macrophages’ led by Professor Dr Jan Rybniker, who heads the Division of Infectious Diseases at University Hospital…

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    News Source: www.sciencedaily.com

  • Adulting is hard on the heart: Teen to young adulthood is a critical time to address risk

    Adulting is hard on the heart: Teen to young adulthood is a critical time to address risk

    Many teenagers enter adulthood with significant risk factors for cardiovascular disease, and the transition from adolescence to adulthood is a key time to address these risk factors and reduce the risk of developing future cardiovascular disease, according to a new American Heart Association scientific statement published today in the Journal of the American Heart Association.

    According to the scientific statement, “Cardiovascular Health in the Transition from Adolescence to Emerging…

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    News Source: www.sciencedaily.com

  • Open-label placebos improve premenstrual syndrome

    Open-label placebos improve premenstrual syndrome

    For many women, the days prior to menstruation are characterized by physical and mental suffering, with abdominal pain, nausea, mood swings, and anxiety. Almost half of women of reproductive age are affected by premenstrual syndrome (PMS), which restricts their everyday well-being and performance. Women with PMS are also more likely to suffer from depression, eating disorders, and migraines and are at a higher risk of suicide.

    Doctors prescribe various medications and supplements to help…

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    News Source: www.sciencedaily.com

  • Remember ebola?

    Remember ebola?

    Six years before the start of the COVID-19 pandemic, an Ebola outbreak in West Africa had people fearing the possibility of a global outbreak. This was the first time many had ever heard of the virus, but since it was first identified in 1976, there have actually been more than 20 serious Ebola incidents. Thankfully, none of them had the global reach of the coronavirus. Ebola has not been eradicated, however. This deadly virus, which causes severe hemorrhagic fever in humans and has a…

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    News Source: www.sciencedaily.com

  • Repetitive behaviors and special interests are more indicative of an autism diagnosis than a lack of social skills

    Repetitive behaviors and special interests are more indicative of an autism diagnosis than a lack of social skills

    People with autism are typically diagnosed by clinical observation and assessment. To deconstruct the clinical decision process, which is often subjective and difficult to describe, researchers used a large language model (LLM) to synthesize the behaviors and observations that are most indicative of an autism diagnosis. Their results, publishing in the Cell Press journal Cell, show that repetitive behaviors, special interests, and perception-based behaviors are most associated with an autism…

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    News Source: www.sciencedaily.com

  • Smart insoles that could change the game for sports and health

    Smart insoles that could change the game for sports and health

    What if your insoles could do more than just cushion your feet? Imagine a pair that could track your movements, help athletes avoid injuries, or even assist doctors in monitoring recovery.

    A new study by scientists at the University of Portsmouth and technology company TG0, funded by Innovate UK via a Knowledge Transfer Partnership (KTP), has brought us closer to making this idea a reality.

    A team of researchers have successfully designed a new smart insole system that can accurately measure…

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    News Source: www.sciencedaily.com