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  • Team finds regional, age-related trends in exposure to drug-resistant pathogen

    Team finds regional, age-related trends in exposure to drug-resistant pathogen

    Campylobacter infections are the most common foodborne illnesses in the U.S., sickening an estimated 1.5 million people each year. A new study examined records of Campylobacter jejuni infections from 10 states, plotting regional, age-related, and drug-resistance trends from 2013 to 2019.

    The study found that drug-resistant C. jejuni infections were highest in the 20-39 age group and that quinolone-resistant C. jejuni infections increased from 22.6% of those tested in 2013 to 33.54% in 2019….

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    News Source: www.sciencedaily.com

  • Scientists call for targeted fiber diets to boost health

    Scientists call for targeted fiber diets to boost health

    Australian food scientists have reclassified dietary fibres — beyond just soluble and insoluble — to better guide nutritional decisions and drive targeted health food products.

    Dietary fibres in fruit, vegetables, beans and whole grains are some of the most important food components for human health. They help digestion, weight management, blood sugar control, heart health, cancer prevention and more.

    But RMIT University food scientist Professor Raj Eri said consumer advice on how best to…

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    News Source: www.sciencedaily.com

  • AI technology improves Parkinson’s diagnoses

    AI technology improves Parkinson’s diagnoses

    Existing research indicates that the accuracy of a Parkinson’s disease diagnosis hovers between 55% and 78% in the first five years of assessment. That’s partly because Parkinson’s sibling movement disorders share similarities, sometimes making a definitive diagnosis initially difficult.

    Although Parkinson’s disease is a well-recognized illness, the term can refer to a variety of conditions, ranging from idiopathic Parkinson’s, the most common type, to other movement disorders like multiple…

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    News Source: www.sciencedaily.com

  • Rethinking how we study the impact of heat on heart health

    Rethinking how we study the impact of heat on heart health

    Scientists have been testing how heat affects our hearts for years. But here’s the thing: the most commonly used method might not provide much insight into what happens to the heart during heat waves.

    A new study led by the University of Ottawa, Human and Environmental Physiology Research Unit with researchers from Harvard University, University of Otago, Institute for Exercise and Environmental Medicine, and the University of Portsmouth, has revealed critical insights into how we test…

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    News Source: www.sciencedaily.com

  • Pregnancy irreversibly remodels the mouse intestine

    Pregnancy irreversibly remodels the mouse intestine

    Researchers at the Francis Crick Institute have found that the small intestine grows in response to pregnancy in mice. This partially irreversible change may help mice support a pregnancy and prepare for a second.

    The organs of many female animals are remodelled by reproduction, but the underlying mechanisms behind the response of the gut to pregnancy have only recently begun to be investigated. For example, scientists previously identified that the fruit fly gut expands during…

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    News Source: www.sciencedaily.com

  • New study challenges assumptions about SEP-1 bundle compliance and sepsis outcomes

    New study challenges assumptions about SEP-1 bundle compliance and sepsis outcomes

    A new study led by the Center for Sepsis Epidemiology and Prevention Studies (SEPSIS) at the Harvard Pilgrim Health Care Institute raises critical questions about the effectiveness of the Centers for Medicare and Medicaid Services’ (CMS) sepsis quality measure, known as the Severe Sepsis/Septic Shock Management Bundle (SEP-1).

    Sepsis, a life-threatening condition arising from dysregulated physiological response to infection, requires rapid treatment to improve survival. In 2015, CMS…

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    News Source: www.sciencedaily.com

  • Earliest stages and possible new cause of stomach cancer revealed

    Earliest stages and possible new cause of stomach cancer revealed

    For the first time, scientists have systematically analysed somatic mutations in stomach lining tissue to unpick mutational processes, some of which can lead to cancer. The team also uncovered hints of a potential new cause of stomach cancer that needs further research.

    Researchers at the Wellcome Sanger Institute, Broad Institute of MIT and Harvard, the University of Hong Kong, and their collaborators sequenced the whole genomes of normal stomach lining samples from people with and without…

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    News Source: www.sciencedaily.com

  • Machine learning aids in detection of ‘brain tsunamis’

    Machine learning aids in detection of ‘brain tsunamis’

    A University of Cincinnati study found machine learning models can aid in the automation and detection of abnormal brain activity sometimes referred to as a “brain tsunami.”

    UC’s Jed Hartings, PhD, is corresponding author of the study published March 12 in the journal Scientific Reports detailing how automation can aid clinicians treating patients with spreading depolarizations (SDs).

    What is a spreading depolarization?

    Hartings said SDs are believed to occur in patients with virtually any…

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    News Source: www.sciencedaily.com

  • Classifying childhood brain cancers by immune response may improve diagnostics and treatments

    Classifying childhood brain cancers by immune response may improve diagnostics and treatments

    Researchers and pediatric neurosurgeons at the University of Pittsburgh School of Medicine and UPMC Children’s Hospital of Pittsburgh developed a new way to profile brain cancers in children, paving the way for improved diagnostics and treatments.

    Today in Science Translational Medicine, researchers describe a diagnostic platform that could classify brain tumors based on the body’s cancer-fighting immune response. This approach, which is complementary to traditional microscopic and genetic…

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    News Source: www.sciencedaily.com

  • New understanding of B cell mutation strategies could have implications for vaccines

    New understanding of B cell mutation strategies could have implications for vaccines

    A vaccine’s ability to generate long-lasting, high-affinity antibodies hinges on a delicate balance. Upon exposure to a vaccine or pathogen, B cells scramble to refine their defenses, rapidly mutating in hopes of generating the most effective antibodies. But each round of this process is a roll of the genetic dice—every mutation has the potential to improve affinity; far more often, however, it degrades or destroys a functional antibody. How do high-affinity B cells ever beat the odds?

    New…

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    News Source: www.sciencedaily.com