Although sedentary behaviour may be an evolutionarily selected trait, it is still important to try to be physically active, says a new study conducted at the University of Jyväskylä, Finland. Researchers have shown for the first time that genetic predisposition to sedentary behaviour is associated with a higher risk of developing the most common cardiovascular diseases. A high genetic predisposition to sedentary behaviour can increase the risk of cardiovascular diseases by up to 20%.
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Genetic predisposition to sedentary behavior increases the risk of cardiovascular diseases
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News Source: www.sciencedaily.com
Discovery of mitochondrial protein opens path to therapeutic advances for heart and Alzheimer’s disease
Calcium transport into and out of mitochondria — the powerhouses of cells — is central to cellular energy production and cell death. To maintain the balance of calcium within these powerhouses, cells rely on a protein known as the mitochondrial sodium-calcium exchanger, or NCLX. Now, in new research, scientists at the Lewis Katz School of Medicine at Temple University have discovered a novel regulator of NCLX activity, a protein called TMEM65, which helps move calcium out of mitochondria,…
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Lactic acid bacteria can improve plant-based dairy alternatives
A new study maps how specific lactic acid bacteria can enhance both the flavour and nutritional quality of plant-based dairy alternatives. The findings may have wide-reaching perspectives for the further development of sustainable foods.
Plant-based dairy alternatives — such as soy, oat, and almond drinks — are produced without animal ingredients for consumers seeking plant-based substitutes for milk and yoghurt. However, many of these products have the similar shortcomings: flavours that…
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Eating only during the daytime could protect people from heart risks of shift work
A study led by researchers at Mass General Brigham suggests that, when it comes to cardiovascular health, food timing could be a bigger risk factor than sleep timing
Numerous studies have shown that working the night shift is associated with serious health risks, including to the heart. However, a new study from Mass General Brigham suggests that eating only during the daytime could help people avoid the health risks associated with shift work. Results are published in Nature Communications….
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Netanyahu: I agreed with Trump to prevent Iran from possessing nuclear weapons.
Israeli Prime Minister Benjamin Netanyahu announced on Tuesday that he …
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Mimicking embryonic growth to break barriers in organoid research
Organoids are made to model human organs and are promising for research and therapy, but there are limitations in their growth and function. A recent study by researchers at The University of Tokyo found that placenta-derived IL1α under hypoxic conditions, can greatly increase growth of human stem cell-derived liver organoids. By promoting liver progenitor cell expansion through a specific signaling pathway, this method offers a promising route to improve organoid models and regenerative…
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Viral ‘backbone’ underlies variation in rotavirus vaccine effectiveness
Researchers have shown that differences in the entire rotavirus genome — not just its two surface proteins — affect how well vaccines work, helping to explain why some strains are more likely to infect vaccinated individuals.
The study, published today as a Reviewed Preprint in eLife, is described by the editors as an important paper. They say the novel approach to estimating rotavirus vaccine effectiveness provides convincing evidence that rotavirus vaccines should be designed based on…
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Even under stress, male-female pairs had each other’s backs
When faced with a potential threat, mice often freeze in place. Moreover, when two animals are together, they typically freeze at the same time, matching each other’s periods of immobility.
In a new study, researchers found that coordination during fear looks different in males and females — and changes when stress is involved.
Male-female mouse pairs consistently stayed in sync during stressful situations, even when the animals were strangers. Same-sex pairs were more likely to fall out of…
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Targeted new approach to treat pancreatic cancer
Researchers at City of Hope®, one of the largest and most advanced cancer research and treatment organizations in the U.S. with its National Medical Center named top 5 in the nation for cancer by U.S. News & World Report, have identified a new molecular target for treating pancreatic cancer, reports a Gastroenterology study published today.
Pancreatic ductal adenocarcinoma (PDAC) is one of the deadliest human cancers worldwide because it evades most treatments. With few therapeutic options,…
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Researchers discover natural compound may slow ALS and dementia
A natural compound found in everyday fruits and vegetables may hold the key to protecting nerve cells — and it’s showing promise as a potential treatment for ALS and dementia, according to new research from the University of Missouri.
“It’s exciting to discover a naturally occurring compound that may help people suffering from ALS or dementia,” Smita Saxena, a professor of physical medicine and rehabilitation at the School of Medicine and lead author of the study, said. “We found this…
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