It’s been recognized for some time that Alzheimer’s disease affects brain regions differently and that tau — a protein known to misbehave — plays an important role in the disease. Normally, tau helps stabilize neurons, but in Alzheimer’s disease, it begins to misfold and tangle inside neurons. It spreads across the brain forming toxic clumps that impair neuronal function and ultimately lead to cell death.
Brain areas like the entorhinal cortex and hippocampus succumb early to tau tangles,…
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News Source: www.sciencedaily.com
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