Scientists at Northwestern University and University of California, Santa Barbara have created the first synthetic fragment of tau protein that acts like a prion. The “mini prion” folds and stacks into strands (or fibrils) of misfolded tau proteins, which then transmit their abnormally folded shape to other normal tau proteins.
Misfolded, prion-like proteins drive the progression of tauopathies, a group of neurodegenerative diseases — including Alzheimer’s disease — characterized by the…
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News Source: www.sciencedaily.com
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