Cancer cells are notoriously flexible, taking on new features as they move around the body. Many of these changes are due to epigenetic modifications, which influence how DNA is packaged, and not due to mutations in the DNA itself. Such modifications are difficult to target for cancer therapy because they are reversible and can flip on and off.
Epigenetic changes have traditionally been thought to arise from internal cellular processes that result in the chemical tagging of DNA and its…
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News Source: www.sciencedaily.com
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