Researchers identify a novel mechanism of fetal anemia linked to mitochondrial protein synthesis deficiency

A researcher team from International Research Center for Medical Sciences (IRCMS) at Kumamoto University, led by Dr. Tatsuya Morishima (Lecturer, Wakakusu researcher at IRCMS), and Prof. Hitoshi Takizawa, has identified a novel mechanism linking fetal anemia to disrupted intracellular iron distribution due to impaired mitochondrial protein synthesis. In this study, a mouse model with a knockout of the mitochondrial tRNA modification enzyme (Mto1) exhibited defective mitochondrial protein…

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News Source: www.sciencedaily.com

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