Why do lymphatic vessels form a jigsaw puzzle-like pattern?

The lymphatic system plays a key role in maintaining the body’s fluid balance and supporting immune defences. Lymphatic vessels are composed of a single layer of endothelial cells, allowing the transfer of fluids, cells and large molecules from surrounding tissues into the vessels. These vessels must be highly permeable to efficiently absorb and transport fluid, while also being flexible enough to withstand sudden changes in tissue fluid volume, such as swelling, without rupture.