Feeling mental exhaustion? These two areas of the brain may control whether people give up or persevere

• Two areas of the brain may work in combination to tell the brain when it’s “feeling” tired.
• People with depression and post-traumatic stress disorder (PTSD) often experience cognitive fatigue.
• Results of the study may provide a way for physicians to better evaluate and treat people who experience such fatigue.

In experiments with healthy volunteers undergoing functional MRI imaging, scientists have found increased activity in two areas of the brain that work together to react to,…