Mitochondrial DNA mutation accumulation may not be a determining factor in aging

Mutations accumulated in mitochondrial DNA associated with aging were earlier believed to cause aging by decreasing the energy-producing function (mitochondrial respiratory function). In this study, researchers at University of Tsukuba demonstrated that mitochondrial respiratory function is not reduced even when wild-type mice accumulated the same level of mutations as premature aging model mice, indicating the need to reinvestigate the conventional theory.

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News Source: www.sciencedaily.com