Potential to prevent and treat a common type of inflammatory arthritis advanced by the identification of new genetic links

In a first-of-its-kind genome-wide association study (GWAS) researchers have discovered two genes, RNF144B and ENPP1, that cause calcium pyrophosphate deposition (CPPD) disease in Americans of European and African descent. This crystalline arthritis is caused by calcium pyrophosphate (CPP) crystal deposition in joints. The findings of this novel study in the Annals of the Rheumatic Diseases, published by Elsevier, open up promising new avenues for targeted prevention and treatment of CPPD…

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News Source: www.sciencedaily.com