Different versions of APOE protein have varying effect on microglia in Alzheimer’s disease

A new study, published today in Nature Communications, offers clues into how APOE isoforms differentially affect human microglia function in Alzheimer’s disease. The study, led by Dr Sarah Marzi and Dr Kitty Murphy at the UK Dementia Research Institute at King’s College London and the Department of Basic and Clinical Neuroscience, underscores the need for new targeted interventions based on APOE genotypes.

Alzheimer’s disease is the most common cause of dementia in the UK, affecting 1 in 14…

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News Source: www.sciencedaily.com

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