Experimental painkiller could outsmart opioids — without the high

The drug, called SBI-810, is part of a new generation of compounds designed to target a receptor on the nerves and spinal cord. While opioids flood multiple cellular pathways indiscriminately, SBI-810, a non-opioid treatment, takes a more focused approach, activating only a specific pain-relief pathway that avoids the euphoric “high” linked to…