A repurposed anti-inflammatory drug may help treat alcohol use disorder and related pain

A preclinical study from scientists at Scripps Research finds that a drug already FDA-approved for treating inflammatory conditions may help reduce both alcohol intake and pain sensitivity — two issues that commonly co-occur with alcohol use disorder (AUD).

The results, published in JCI Insight on April 22, 2025, suggest that the drug apremilast — a phosphodiesterase-4 (PDE4) inhibitor, or a compound that blocks an enzyme involved in inflammation — could be repurposed as a dual-acting…

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News Source: www.sciencedaily.com

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